The penis is composed of the following structures: Two parallel columns of spongy tissue called the corpus cavernosa, or erectile
bodies. A central spongy chamber called the corpus spongiosum, which contains the urethra, the tube that carries urine from the bladder through the penis. These structures
are made up of erectile tissue. Erectile tissue is rich in tiny pools of blood vessels called cavernous sinuses. Each of these vessels are surrounded by smooth muscles and
supported by elastic fibrous tissue composed of a protein called collagen.
Erectile Function and Nitric Oxide:
The penis is either flaccid or erect depending on the state of arousal. In the flaccid, or unerect, penis, the following normally occurs: Small arteries leading to the cavernous sinuses contract, reducing the inflow of blood. The smooth muscles regulating the many tiny blood vessels also stay contracted, limiting the amount of blood that can collect in the penis.
During arousal the following occurs:
The man's central nervous system stimulates the release of a number of chemicals, including nitric oxide, which is now considered the main contributor for eliciting and maintaining erection. Nitric oxide stimulates production of cyclic GMP, a chemical that relaxes the smooth muscles in the penis. This allows blood to flow into the tiny pool- like cavernous sinuses, flooding the penis. This increased blood flow nearly doubles the diameter of the spongy chambers. The veins surrounding the chambers are squeezed almost completely shut by this pressure. The veins are unable to drain blood out of the penis and so the penis becomes rigid and erect. After ejaculation or arousal, cyclic GMP is broken down by an enzyme called phosphodiesterase-5 (PDE5), and other compounds are released that cause the penis to become flaccid (unerect) again.
Vascular Disease and Erectile Dysfunction
Vascular diseases are those that affect the blood vessels. These diseases restrict blood flow to organs such as the heart, brain, and kidneys. In cases of erectile dysfunction ED), vascular diseases restrict blood flow to the penis. Fifty to as much of 70 percent of erectile dysfunction cases are caused by vascular disease.
More About Vascular Disease:
Restriction of blood flow can occur because of a buildup of cholesterol and other substances that may block blood vessels. It also is known that blood vessels open more widely (relax or dilate) or close down to become narrower (constrict), possibly due to signals from cells called endothelial cells that are located inside the lining of these blood vessels. These signals can result in the restriction of blood flow to certain organs even without the vessels’ necessarily being clogged by any material. When endothelial function is impaired, constriction that is similar to plugged blood vessels may result. This could be one explanation why ED is so commonly associated with vascular disease.
Conditions associated with vascular disease:
The following conditions are associated with vascular disease:
➤ Coronary artery disease
Peripheral vascular disease. This disease particularly affects blood vessels that supply blood to the lower extremities.
Factors in vascular disease:
The following conditions make vascular disease worse and likely contribute to ED:
➤ High cholesterol
➤ Cigarette smoking
What is venous leak?
If the veins in the penis cannot prevent blood from leaving the penis during an erection, an erection cannot be maintained. This condition is known as a venous leak. Venous leakage may occur with vascular disease, but it also can occur as a result of poor smooth muscle relaxation of the penis. Difficulty with smooth muscle relaxation of the penis can occur with diabetes or with Peyronie’s Disease, a condition that results in the build-up of scar tissue of the sheath surrounding the erection tissue. Venous leak also can occur when neurological diseases or high levels of anxiety are present because these conditions can prevent adequate smooth muscle relaxation.
Important Substances for Erectile Health
A proper balance of certain chemicals, gases, and other substances is critical for erectile health:
Collagen: The protein collagen is the major component in structural tissue in the body, including in the penis. Excessive amounts, however, form scar tissue, which can impair erectile function.
Oxygen: Oxygen-rich blood is one of the most important components for erectile health. Oxygen affects two substances that are important in achieving erection:
➤ Oxygen suppresses transforming growth factor beta 1 (TGF-B1). TGF-B1 is a component of the immune system called a cytokine and is produced by smooth muscle cells. It appears to stimulate collagen production in the corpus cavernosum, which can lead to erectile dysfunction.
➤ Oxygen enhances the activity of prostaglandin E1. Prostaglandin E1 is produced during erection by the muscle cells in the penis. It activates an enzyme that initiates calcium release by the smooth muscle cells, which relaxes them and allows blood flow. Prostaglandin E1 also suppresses production of collagen.
➤ Oxygen levels vary widely from reduced levels in the flaccid state to very high in the erect state. During sleep, oxygen levels are high and a man can normally have three to five erections per night, each one lasting from 20 to 40 minutes.
Testosterone and Other Hormones
Normal levels of hormones, especially testosterone, are essential for erectile function, though their exact role is not clear.
Erectile Dysfunction and Oxygen Deprivation
Erectile dysfunction most commonly occurs when the penis is deprived of oxygen-rich blood. When oxygen levels to the penis are low, an imbalance occurs in two important substances, TGF-B1 and prostaglandin E1:
➤ TGF-B1 levels increase, which trigger production of collagen, a tough protein that forms all types of connective tissue, including scar tissue.
➤ In addition, there is a reduction in prostaglandin E1, a chemical that suppresses collagen production and relaxes the smooth muscles to allow blood flow resulting in an erection.
➤ When TGF-B1 levels increase and prostaglandin E1 levels decrease, smooth muscles waste away and collagen is overproduced, causing scarring, loss of elasticity, and reduced blood flow to the penis. A number of conditions can deprive the penis of oxygen-rich blood.
Blockage of Blood Vessels (Ischemia)
The primary cause of oxygen deprivation is ischemia--the blockage of blood vessels. The same conditions that cause blockage in the blood vessels leading to heart problems may also contribute to erectile dysfunction. For example, when cholesterol and other factors are imbalanced, a fatty substance called plaque forms on artery walls. As the plaque builds up, the arterial walls gradually narrow, reducing blood flow. This process, known as atherosclerosis, is the major contributor to the development of coronary heart disease. It may also play a role in the development of erectile dysfunction.
Impotency and Cholesterol
In a totally unrelated development (unrelated to aging, that is), National Institute of Aging supported scientists from the University of South Carolina have found yet another compelling reason to avoid cholesterol. Men with lower blood cholesterol or higher amounts of the beneficial high-density lipoprotein (HDL) cholesterol may be less likely to develop erectile dysfunction or impotence. According to the researchers, atherosclerosis (hardening of the arteries), which may impede blood flow to and from the penis, is one primary cause of impotence. While a positive link between blood cholesterol and atherosclerosis, the association between cholesterol and impotence has only been suggested until now. The South Carolina scientists conducted a study of more than 3,200 generally healthy men between the ages of 25 and 83. Data indicated that the men with total cholesterol over 240 milligrams per deciliter (mg/dl) of blood had nearly double the risk of penile dysfunction as men with readings of 180 mg/dl. A similar pattern held true in patients with significant amounts of HDL cholesterol. Those with HDL readings of 60 mg/dl or greater were one-third less likely to develop dysfunction than were men with less than 30 mg/dl HDL.
Penis Vessels Blockage Therapy
Our Herbal penis vessels blockage Therapy enables many men suffering from penis vessels blockage to react to sexual stimulation. At the time a gentleman is sexually aroused, the blood vessels within the penis relax and broaden, allowing more blood to circulate into the penis. When the arteries in the penis get bigger and then harden, the veins that ordinarily carry blood away from the penis get compressed, restricting the circulation away from of the penis. Our penis vessels blockage Therapy allows for an increased amount of blood to flow fashionable and less to flow out, causing the penis to grow, and resulting in an erection. Benefits and drawbacks of our Therapy in the role of a remedy for blood vessels blockage are reviewed as follows:
➤ Penis vessels blockage Therapy is effective. It has been proved to function as a helpful therapy of penis vessels blockage. Development in erectile response was reported from fifty percent to eighty-eight percent of patients.
➤ The effects of this treatment are primarily transient and slight. Herbal safety has been evaluated for greater than three thousand seven hundred patients.
➤ The therapy by means of sexual meds is non-invasive.
➤ Unlike vacuum pumps that may result in a "cold penis" experience for the partner, therapy by means of sexual medication helps the man reach stiffer erections.
Treatment for penis vessels blockage by Dr. Hakeem Tariq Mehmood Taseer
Pure herbal treatment by Dr. Hakeem Tariq Mehmood Taseer to cure penis vessels blockage with well proven results. Has a very high success rate in treating different causes of penis vessels blockage . Dosage and duration of the treatment may vary as per the patient profile. Treatment is without any side effects.
|TASEER PENIS ENLARGEMENTS (RECOMMENDED THERAPIES)|
|01-Barki Massage||02-Regular Penis Enlargement||03-Fast Penis Enlargement|
|04-More Fast Penis Enlargement||05-Speedy Penis Enlargement||06-More Speedy Penis Enlargement|
|07-Advance Penis Enlargement||08-Max-Improved Penis Enlargement||09-Fast Action Penis Enlargement|
|10-Fast Moving Peins Enlargement||11-Bronze Penis Enlargement||12-Silver Penis Enlargement|
|13-Gold Penis Enlargement||14-Platinum Penis Enlargement||15-Diamond Extra Penis Enlargement|
|16-Tilla Matwal (Khas-ul-Khas)|